{"id":131516,"date":"2013-03-07T11:50:24","date_gmt":"2013-03-07T09:50:24","guid":{"rendered":"http:\/\/www.nationalturk.com\/?p=131516"},"modified":"2013-03-07T11:53:04","modified_gmt":"2013-03-07T09:53:04","slug":"beyni-genclestiren-genetik-anahtar-bulundu-131516","status":"publish","type":"post","link":"https:\/\/www.nationalturk.com\/tr\/beyni-genclestiren-genetik-anahtar-bulundu-131516\/","title":{"rendered":"Beyni gen\u00e7le\u015ftiren genetik anahtar bulundu!"},"content":{"rendered":"

\"\"Amerikal\u0131 bilim adamlar\u0131, eri\u015fkin farelerin beyninin gen\u00e7le\u015fmesini sa\u011flayan genetik anahtar\u0131 buldu.<\/h1>\n

Nogo Resept\u00f6r 1 ad\u0131 verilen genin i\u015flevini devre d\u0131\u015f\u0131 b\u0131rakan ABD’deki Yale T\u0131p Okulu’ndan bilim adamlar\u0131, eri\u015fkin farelerin beyinlerini gen\u00e7le\u015ftirerek \u00f6\u011frenme ve beyin hasarlar\u0131nda iyile\u015fme s\u00fcrecini h\u0131zland\u0131rmay\u0131 ba\u015fard\u0131.<\/p>\n

Ara\u015ft\u0131rmac\u0131lar, bu yolla insanlarda da beyin hasarlar\u0131nda daha \u00e7abuk iyile\u015fme sa\u011flanabilece\u011fine dikkati \u00e7ekti.<\/p>\n

Profes\u00f6r Stephen Strittmatter ba\u015fkanl\u0131\u011f\u0131ndaki bilim ekibince yap\u0131lan \u00e7al\u0131\u015fma, Neuron adl\u0131 bilimsel dergide yay\u0131mland\u0131.
\nAylar s\u00fcren \u00e7al\u0131\u015fmada beynin ya\u015flanmas\u0131ndaki ana genetik anahtar olan Nogo Resept\u00f6r 1 genini tan\u0131mlayan ara\u015ft\u0131rmac\u0131lar, bu genin, beyinde, n\u00f6ronlar aras\u0131nda bulunan sinaptik ba\u011flant\u0131lardaki h\u0131zl\u0131 de\u011fi\u015fiklikleri yava\u015flatarak ergen beyninin elastikiyetini bask\u0131lad\u0131\u011f\u0131n\u0131 ve eri\u015fkinlikte beynin, eskiye g\u00f6re daha dura\u011fan bir esneklikte kalmas\u0131na neden oldu\u011funu ortaya koydu.<\/p>\n

Bu genin bulunmad\u0131\u011f\u0131 farelerde beyindeki esnekli\u011fin eri\u015fkinlikte de s\u00fcrd\u00fc\u011f\u00fcn\u00fc belirleyen bilim adamlar\u0131, bu genin i\u015flevinin devre d\u0131\u015f\u0131 b\u0131rak\u0131ld\u0131\u011f\u0131 eri\u015fkin farelerin beyinlerindeki esneklik d\u00fczeyinin ergenlikteki seviyesine \u00e7\u0131kt\u0131\u011f\u0131n\u0131 g\u00f6zlemledi.<\/p>\n

Ara\u015ft\u0131rmac\u0131lar, yapt\u0131klar\u0131 deneyde genin bulunmad\u0131\u011f\u0131 farelerde beyin yaralanmalar\u0131nda iyile\u015fmenin gen\u00e7 farelerdeki kadar h\u0131zl\u0131 oldu\u011funu. Ayr\u0131ca bu farelerin yeni ve karma\u015f\u0131k motor g\u00f6revlerini yerine getirmede eri\u015fkinlere g\u00f6re daha \u00e7abuk ustala\u015fabildiklerini g\u00f6zlemledi.<\/p>\n

Beyinde olu\u015fan hasar nedeniyle hastalar, rehabilitasyon devresinde ellerini hareket ettirebilmek gibi g\u00f6revleri yeniden \u00f6\u011frenmek zorunda kal\u0131yor. Rehabilitasyonda gen\u00e7 hastalar\u0131n eri\u015fkinlere g\u00f6re daha h\u0131zl\u0131 geli\u015fme kaydetti\u011fi biliniyor.
\nBilimsel \u00e7al\u0131\u015fman\u0131n yaz\u0131 heyetinde yer alan Yale \u00dcniversitesi doktora \u00f6\u011frencisi Feras Akbik, “Bu, Nogo Resept\u00f6r geniyle oynaman\u0131n, insanlarda, inme gibi beyin hasarlar\u0131nda rehabilitasyonu h\u0131zland\u0131rma ve daha iyi seviyeye getirme potansiyeli ta\u015f\u0131d\u0131\u011f\u0131n\u0131 g\u00f6steriyor” dedi.<\/p>\n

Ara\u015ft\u0131rmac\u0131lar ayr\u0131ca, bu genin bulunmad\u0131\u011f\u0131 farelerin gergin an\u0131lar\u0131n\u0131 daha h\u0131zl\u0131 unuttu\u011funu tespit ettiklerini s\u00f6yleyerek, bunun, genle oynanarak Travma Sonras\u0131 Stres Bozuklu\u011fu tedavisine katk\u0131 sa\u011flanabilece\u011fine i\u015faret etti\u011fini vurgulad\u0131.
\nAra\u015ft\u0131rma National Institutes of Health adl\u0131 ABD h\u00fck\u00fcmetine ba\u011fl\u0131 bir kurulu\u015fun maddi katk\u0131s\u0131yla yap\u0131ld\u0131.<\/p>\n\n","protected":false},"excerpt":{"rendered":"

Amerikal\u0131 bilim adamlar\u0131, eri\u015fkin farelerin beyninin gen\u00e7le\u015fmesini sa\u011flayan genetik anahtar\u0131 buldu.<\/p>\n","protected":false},"author":4,"featured_media":131518,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6768,6665,6155,5005,6669],"tags":[1887,91821],"class_list":["post-131516","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-amerika","category-dunya","category-gundem","category-manset","category-saglik","tag-abd","tag-beyin"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts\/131516","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/comments?post=131516"}],"version-history":[{"count":0,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts\/131516\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/media\/131518"}],"wp:attachment":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/media?parent=131516"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/categories?post=131516"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/tags?post=131516"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}