{"id":166084,"date":"2014-05-26T13:50:26","date_gmt":"2014-05-26T10:50:26","guid":{"rendered":"http:\/\/www.nationalturk.com\/?p=166084"},"modified":"2014-05-26T13:50:26","modified_gmt":"2014-05-26T10:50:26","slug":"dunya-kuba-uretilen-bu-asiyi-bekliyor-166084","status":"publish","type":"post","link":"https:\/\/www.nationalturk.com\/tr\/dunya-kuba-uretilen-bu-asiyi-bekliyor-166084\/","title":{"rendered":"D\u00fcnya, K\u00fcba’da \u00fcretilen bu a\u015f\u0131y\u0131 bekliyor"},"content":{"rendered":"

\"kuba-akciger-asisi\"<\/a>D\u00fcnyada her y\u0131l \u00e7ok say\u0131da ki\u015finin hayat\u0131n\u0131 kaybetmesine yol a\u00e7an akci\u011fer kanserine y\u00f6nelik K\u00fcba’da geli\u015ftirilen ve klinik ara\u015ft\u0131rmalar kapsam\u0131nda hastalara uygulanan a\u015f\u0131da sona yakla\u015f\u0131ld\u0131.<\/h1>\n

A\u015f\u0131n\u0131n g\u00f6n\u00fcll\u00fc hastalara yap\u0131lan uygulamas\u0131na ili\u015fkin Faz 3 sonu\u00e7lar\u0131, 2015 y\u0131l\u0131nda a\u00e7\u0131klanacak.<\/p>\n

Havana Molek\u00fcler \u0130mmunuloji Merkezi (CIM) Molek\u00fcler \u0130mmunoloji Enstit\u00fcs\u00fc \u0130novasyon Direkt\u00f6r\u00fc Luis Enrique Fernandez Molina, yapt\u0131\u011f\u0131 a\u00e7\u0131klamada, K\u00fcba’da, D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fcn\u00fcn (DS\u00d6) tavsiyeleri do\u011frultusunda geni\u015f kapsaml\u0131 ulusal bir plan\u0131n y\u00fcr\u00fcrl\u00fc\u011fe konuldu\u011funu ve a\u015f\u0131 \u00e7al\u0131\u015fmalar\u0131na a\u011f\u0131rl\u0131k verildi\u011fini s\u00f6yledi.<\/p>\n

Yakla\u015f\u0131k 30 y\u0131ld\u0131r bu ama\u00e7la biyoteknoloji konusunda, \u00f6nemli yat\u0131r\u0131mlar ger\u00e7ekle\u015ftirdi\u011fini ve yakla\u015f\u0131k bir milyar Amerikan dolar\u0131n ara\u015ft\u0131rma ve geli\u015ftirmeye ayr\u0131ld\u0131\u011f\u0131n\u0131 dile getiren Molina, \u00fclkelerinde \u00f6zellikle akci\u011fer kanserinin g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131n\u0131n \u00e7ok y\u00fcksek oldu\u011funu belirtti.<\/p>\n

CIM taraf\u0131ndan geli\u015ftirilen ilk akci\u011fer kanseri a\u015f\u0131s\u0131n\u0131n 2008 y\u0131l\u0131nda ruhsatland\u0131r\u0131ld\u0131\u011f\u0131n\u0131 ve 2013 y\u0131l\u0131nda ise ikinci a\u015f\u0131 Racotumomab’\u0131n\u0131n (Vaxira) yine ayn\u0131 merkez taraf\u0131ndan geli\u015ftirildi\u011fini anlatan Molina, bu \u00fcr\u00fcn\u00fcn de ruhsatlanarak bug\u00fcne kadar 600’dan fazla hastada kullan\u0131ld\u0131\u011f\u0131n\u0131 s\u00f6yledi. S\u00f6z konusu a\u015f\u0131n\u0131n, “Arjantin’de de ruhsatl\u0131 olarak 2013 Temmuz ay\u0131ndan bu yana kullan\u0131ld\u0131\u011f\u0131n\u0131” ifade eden Molina, K\u00fcba’daki t\u00fcm kliniklerde ilac\u0131n \u00fccretsiz olarak kullan\u0131mda bulundu\u011funu aktard\u0131. Molina, “Peru, bu konuda K\u00fcba h\u00fck\u00fcmeti ile g\u00f6r\u00fc\u015fmeye ba\u015flayan ilk \u00fclke oldu. ABD\u2019de ise ilac\u0131n yaln\u0131z klinik \u00e7al\u0131\u015fmalar i\u00e7in kullan\u0131m\u0131 m\u00fcmk\u00fcn” a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n

Molina, a\u015f\u0131n\u0131n bile\u015feninde t\u00fcm\u00f6r antijenlerinin bulundu\u011funu belirterek, “Kanserli t\u00fcm\u00f6r ile ilgili molek\u00fcl\u00fc buluyorsunuz ve t\u00fcm\u00f6re \u00f6zel a\u015f\u0131 haz\u0131rl\u0131yorsunuz. A\u015f\u0131 da sadece t\u00fcm\u00f6re sald\u0131r\u0131yor” dedi.<\/p>\n\n

“A\u015f\u0131 ile ilgili klinik \u00e7al\u0131\u015fmalar\u0131n son a\u015famada oldu\u011funu” vurgulayan Molina, “\u2019Latin Amerika, Meksika, Kuzey Amerika’n\u0131n baz\u0131 b\u00f6lgelerinde, baz\u0131 Asya \u00fclkelerinde klinik deneyler s\u00fcr\u00fcyor. Bu son a\u015famadaki klinik \u00e7al\u0131\u015fmalara binden fazla insan dahil. Bug\u00fcne kadar hi\u00e7bir yan etki ile kar\u015f\u0131la\u015fmad\u0131k, hastalar\u0131n genel durumunda iyiye gidi\u015f s\u00f6z konusu. Ama bu yava\u015f i\u015fleyen bir s\u00fcre\u00e7. \u015eunu unutmamak gerekir bu hastalar ileri derecede akci\u011fer kanseri hastalar\u0131. O y\u00fczden bu hastal\u0131k kaybolup gitmeyecek. Hastalar\u0131n y\u00fczde 20’sinde sa\u011fkal\u0131m\u0131 g\u00f6r\u00fcyoruz. A\u015f\u0131n\u0131n g\u00f6n\u00fcll\u00fc hastalara yap\u0131lan uygulamas\u0131na ili\u015fkin Faz 3 sonu\u00e7lar\u0131 2015 y\u0131l\u0131nda a\u00e7\u0131klanacak” a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n

Baz\u0131 T\u00fcrk bilim insanlar\u0131n\u0131n s\u00f6z konusu a\u015f\u0131n\u0131n sonu\u00e7lar\u0131n\u0131 “tatmin edici bulmad\u0131klar\u0131na” y\u00f6nelik ele\u015ftirilerini de de\u011ferlendiren Molina, “Akci\u011fer kanseri a\u015f\u0131s\u0131n\u0131n en tehlikeli k\u0131sm\u0131 ismi. \u00c7\u00fcnk\u00fc, a\u015f\u0131 koruyan bir \u015fey gibi g\u00f6z\u00fck\u00fcr, ama akci\u011fer kanserinde \u00f6nleyici a\u015f\u0131 yoktur. \u00c7\u00fcnk\u00fc, a\u015f\u0131 e\u015fittir sigara i\u00e7memektir” diye konu\u015ftu.<\/p>\n

“Kanser i\u00e7in evrensel bir a\u015f\u0131 yok”<\/p>\n

“ABD h\u00fck\u00fcmetinin s\u00fcrd\u00fcrd\u00fc\u011f\u00fc K\u00fcba’ya kar\u015f\u0131 ambargo, hem Amerikan G\u0131da ve \u0130la\u00e7 Dairesi-FDA onay\u0131 ile ilac\u0131n yayg\u0131n kullan\u0131ma girmesinin, hem de hasta ABD vatanda\u015flar\u0131n\u0131n K\u00fcba kliniklerinde tedavi almas\u0131n\u0131n \u00f6n\u00fcnde engel te\u015fkil ediyor” iddias\u0131nda bulunan Molina, yap\u0131lan \u00e7al\u0131\u015fmalar\u0131n bilimsel ara\u015ft\u0131rmalara dayand\u0131\u011f\u0131n\u0131 ve ama\u00e7lar\u0131n\u0131n bundan kar sa\u011flamak de\u011fil, insanlar\u0131 ilaca kolay eri\u015febilir hale getirmek ve ya\u015fam kalitelerini art\u0131rmak oldu\u011funu vurgulad\u0131.<\/p>\n

K\u00fcba’da yap\u0131lan \u00e7al\u0131\u015fmalar\u0131n baz\u0131lar\u0131n\u0131n ABD’deki klinik \u00e7al\u0131\u015fmalarda yer ald\u0131\u011f\u0131n\u0131 anlatan Molina, “Ambargo var, ama Amerikan t\u0131p \u00e7evreleri buna izin veriyor. Sonu\u00e7lar iyi geldik\u00e7e bilim \u00e7evreleri de olumlu sonu\u00e7lar\u0131n\u0131 anlayacak” dedi.<\/p>\n

Molina, T\u00fcrkiye’de de bu \u00fcr\u00fcnlerle ilgili bilimsel \u00e7al\u0131\u015fmalar\u0131n sonu\u00e7lar\u0131n\u0131, ila\u00e7lar\u0131n geli\u015ftirildi\u011fi Molek\u00fcler \u0130mmunoloji Merkezinden gelen Dr. Tania Crombet taraf\u0131ndan Ocak 2014 tarihinde \u0130mmuno Onkoloji Derne\u011fi ile ger\u00e7ekle\u015fen toplant\u0131larda sunuldu ve bilim insanlar\u0131 taraf\u0131ndan her y\u00f6n\u00fcyle tart\u0131\u015f\u0131ld\u0131\u011f\u0131n\u0131 dile getirdi.<\/p>\n

“Burada \u00fcst\u00fcnde vurgulanmas\u0131 gereken, kanser i\u00e7in evrensel bir a\u015f\u0131n\u0131n olmad\u0131\u011f\u0131d\u0131r. \u015eu an i\u00e7in onkolojide uygulanacak a\u015f\u0131lar, kanser geli\u015fimini \u00f6nleyen de\u011fil, tedavi edilmesine yard\u0131mc\u0131 olan a\u015f\u0131lard\u0131r” vurgusunda bulunan Molina, bunlar\u0131n t\u0131bbi literat\u00fcrde “terap\u00f6tik kanser a\u015f\u0131s\u0131” olarak isimlendirildi\u011fini s\u00f6yledi. Molina, “\u0130\u015flem olarak t\u00fcm\u00f6r\u00fcn kendisi veya bile\u015fenleri, kanserli ki\u015fiden al\u0131n\u0131r, laboratuvar ortam\u0131nda haz\u0131rlan\u0131r ve ki\u015fiye, ba\u011f\u0131\u015f\u0131kl\u0131k sistemini uyarmas\u0131 ve t\u00fcm\u00f6r\u00fcn tan\u0131nmas\u0131na yard\u0131mc\u0131 olmas\u0131 amac\u0131yla tekrar geri verilir” a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n\n","protected":false},"excerpt":{"rendered":"

D\u00fcnyada her y\u0131l \u00e7ok say\u0131da ki\u015finin hayat\u0131n\u0131 kaybetmesine yol a\u00e7an akci\u011fer kanserine y\u00f6nelik K\u00fcba’da geli\u015ftirilen ve klinik ara\u015ft\u0131rmalar kapsam\u0131nda hastalara uygulanan a\u015f\u0131da sona yakla\u015f\u0131ld\u0131.<\/p>\n","protected":false},"author":3,"featured_media":174359,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6665,6771,6669],"tags":[19121,162795,162796,14,162793,160,54865,162792,569],"class_list":["post-166084","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya","category-latin-amerika","category-saglik","tag-akciger-kanseri","tag-akciger-kanseri-asisi","tag-akciger-kanseri-tedavi","tag-kuba","tag-kuba-akciger-kanseri","tag-kuba-havana","tag-kuba-kanser","tag-kuba-kanser-asisi","tag-kuba-saglik"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts\/166084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/comments?post=166084"}],"version-history":[{"count":0,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/posts\/166084\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/media\/174359"}],"wp:attachment":[{"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/media?parent=166084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/categories?post=166084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nationalturk.com\/tr\/wp-json\/wp\/v2\/tags?post=166084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}